en Treatment stategies with herbal or others Treatment stategies with herbal or others پژوهشي Original research papers <div style="text-align: justify;">This research was carried out to survey the ffects of dietary of <em>Lentinula edodes</em> mushroom extract as a feed supplement on growth performance and survival rate, immune response, hematological and biochemical characteristics of beluga juvenile (<em>Huso huso</em>). Four hundred and fifty fish after acclimation with average weight of 40.45 &plusmn; 5.72 g were fed in a wholly randomized design in 5 treatments (basic diet containing 0% (control), 00.5%, 1%, 1.5% and 2% <em>L. edodes </em>mushroom &nbsp;extract) and 3 replicates. During the experiment (56 days), a total of eight samples were taken in 8 weeks. The mean of data were analyzed using one-way ANOVA and Duncan&#39;s post hoc test at 5% level. Results indicated that administration of 2% of mushroom extract for 8 weeks improved weight gain, specific growth rate and feed conversion ratio of beluga (P<0.05). Among the investigated hematological indices, Supplementing 2% <em>L. edodes</em> resulted in increased levels of the erythrocytes (RBC), hemoglobin (Hb), haematocrit (Hct) in comparison with the control group (P<0.05). At the end of the assay, there were significant decreased in some of the biochemical parameters (Cholesterol, alkaline phosphatase (ALP) and alanine aminotransferase (ALT)) in the treatments containing mashroom extract (P <0.05). Also the activity of serum lysozyme activity and superoxide dismutase (SOD) Among immune parameters studied were increased in group of 2% of <em>L. edodes</em> compared to other treatments (P <0.05). These results indicated that the addition of supplemental mashroom extracts, especially at 2% level to the beluga juveniles diet, were improved the growth performance, some hematological and biochemical parameters and immune response of beluga juvenile.<br> <br> &nbsp;</div> Hemato-immunological parameters, growth, Huso huso, Lentinula edodes (mushroom) extract 29 48 http://ijaah.ir/browse.php?a_code=A-10-173-2&slc_lang=en&sid=1 H Chitsaz حسین چیت ساز chitsaz2@gmail.com 10031947532846001829 10031947532846001829 Yes Department of Fisheries, Azadshahr Branch, Islamic Azad University, Azadshahr, Iran عضو هیات علمی گروه شیلات، واحد آزادشهر، دانشگاه آزاد اسلامی، آزادشهر، ایران R Akrami رضا اکرمی akrami.aqua@gmail.com 10031947532846001830 10031947532846001830 No Department of Fisheries, Azadshahr Branch, Islamic Azad University, Azadshahr, Iran دانشیار گروه شیلات، واحد آزادشهر، دانشگاه آزاد اسلامی، آزادشهر، ایران Z Ahmadi زید احمدی cd_da@ymail.com 10031947532846001831 10031947532846001831 No Department of Fisheries, Azadshahr Branch, Islamic Azad University, Azadshahr, Iran عضو هیات علمی گروه شیلات، واحد آزادشهر، دانشگاه آزاد اسلامی، آزادشهر، ایران