en Aquaculture and Health management Aquaculture and Health management پژوهشي Original research papers <span style="font-size:11pt"><span style="line-height:120%"><span style="font-family:Calibri,sans-serif"><span lang="TR" style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">In this study,</span></span></span></span><span style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black"> efficacy of</span></span></span></span><span lang="TR" style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black"> two main probiotics (</span></span></span></span><i><span style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">Citrobacter</span></span></span></span></i><i> </i><i><span style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">freundii</span></span></span></span></i><span lang="TR" style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black"> and</span></span></span></span><i><span style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black"> Bacillus</span></span></span></span></i><i> </i><i><span style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">foraminis</span></span></span></span></i><span lang="TR" style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">)</span></span></span></span> <span lang="TR" style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">with </span></span></span></span><span style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">indigenous</span></span></span></span><span lang="TR" style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black"> quorum quenching (QQ) isolated from the intestine of </span></span></span></span><i><span style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">Cyprinus</span></span></span></span></i><i> </i><i><span style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">carpio</span></span></span></span></i> <span style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">was studied on</span></span></span></span><span lang="TR" style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black"> haemato-innate immune responses, antioxidant</span></span></span></span> <span lang="TR" style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">capacity and disease resistance of</span></span></span></span><i> </i><span style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">this fish species<i>.</i></span></span></span></span><span lang="TR" style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black"> Juveniles of </span></span></span></span><i><span style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">C.</span></span></span></span></i><i> </i><i><span style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">carpio</span></span></span></span></i><span lang="TR" style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black"> (n=</span></span></span></span><span style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">450</span></span></span></span><span lang="TR" style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">, weighing </span></span></span></span><span style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">50</span></span></span></span><span lang="TR" style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">&plusmn;10 g) were randomly divided into </span></span></span></span><span style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">6</span></span></span></span><span lang="TR" style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black"> equal groups (with 3 replications) and</span></span></span></span><span style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black"> were</span></span></span></span><span lang="TR" style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black"> fed on diets containing </span></span></span></span><span style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">1</span></span></span></span><span lang="TR" style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">&times;10</span></span></span></span>^{<span style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">9</span></span></span></span>}<span lang="TR" style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black"> cfu g^-1 of </span></span></span></span><i><span style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">C.</span></span></span></span></i><i> </i><i><span style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">freundii</span></span></span></span></i><span lang="TR" style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black"> (</span></span></span></span><span style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">QQ1, G1</span></span></span></span><span lang="TR" style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">), </span></span></span></span><i><span style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">B.</span></span></span></span></i><i> </i><i><span style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">foraminis</span></span></span></span></i><span lang="TR" style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black"> (</span></span></span></span><span style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">QQ2,r G2</span></span></span></span><span lang="TR" style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">), <i>L. plantarum</i> (</span></span></span></span><span style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">without characteristics QQ, WQQ, G3</span></span></span></span><span lang="TR" style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">)</span></span></span></span><span style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">, QQ1</span></span></span></span> <span style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">+</span></span></span></span> <span style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">QQ2 </span></span></span></span><span lang="TR" style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">(G</span></span></span></span><span style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">4</span></span></span></span><span lang="TR" style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">)</span></span></span></span><span style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">, QQ1</span></span></span></span> <span style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">+</span></span></span></span> <span style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">QQ2+WQQ </span></span></span></span><span lang="TR" style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">(</span></span></span></span><span style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">combine, </span></span></span></span><span lang="TR" style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">G</span></span></span></span><span style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">5</span></span></span></span><span lang="TR" style="font-size:12.0pt"><span style="line-height:120%"><span new="" roman="" style="font-family:" times=""><span style="color:black">), and a control diet (without probiotic) for 60 continuous days. </span></span></span></span></span></span></span><br> <span style="font-size:12.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black">Our results showed,</span></span></span><span lang="TR" style="font-size:12.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black"> alkaline phosphatase (ALP) levels increased in QQ2 at 30 days but </span></span></span><span style="font-size:12.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black">it </span></span></span><span lang="TR" style="font-size:12.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black">declined later, while AST and ALT activities varied among treatments. Serum triglycerides, </span></span></span><span style="font-size:12.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black">Total protein, albumin, </span></span></span><span lang="TR" style="font-size:12.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black">Glucose</span></span></span> <span style="font-size:12.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black">&nbsp;and urea </span></span></span><span lang="TR" style="font-size:12.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black">were significantly </span></span></span><span style="font-size:12.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black">different</span></span></span><span lang="TR" style="font-size:12.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black"> in the probiotic treatments </span></span></span><span style="font-size:12.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black">compared</span></span></span> <span style="font-size:12.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black">control</span></span></span><span lang="TR" style="font-size:12.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black"> group (<i>p</i><0.05).</span></span></span> <span lang="TR" style="font-size:12.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black">Overall, </span></span></span><span style="font-size:12.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black">indigenous </span></span></span><span lang="TR" style="font-size:12.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black">probiotics improved various health parameters and reduced </span></span></span><span style="font-size:12.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black">side effects in treated</span></span></span><span lang="TR" style="font-size:12.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black"> fish</span></span></span> C. carpio, Intestine bacteria, Indigenous quorum quenching, Biochemical factors 13 34 http://ijaah.ir/browse.php?a_code=A-10-144-2&slc_lang=en&sid=1 M.A. Abdulaziz mahir.aldafter@gmail.com 10031947532846003168 10031947532846003168 Yes Shahid Chamran University of Ahvaz T. Mohammadian t.mohammadian@scu.ac.ir 10031947532846003169 10031947532846003169 No Shahid Chamran University of Ahvaz M. Mesbah m.mesbah@scu.ac.ir 10031947532846003170 10031947532846003170 No Shahid Chamran University of Ahvaz D. Gharibi d.gharibi@scu.ac.ir 10031947532846003171 10031947532846003171 No Shahid Chamran University of Ahvaz S.M. Jalali mi.jalali@scu.ac.ir 10031947532846003172 10031947532846003172 No Shahid Chamran University of Ahvaz