:: Volume 5, Issue 2 (2019) ::
Sustainable Aquaculture. Health. Management. J. 2019, 5(2): 12-21 Back to browse issues page
Study on anesthetic effects of Ketamine and Acepromazine in Tor grypus
M Alishahi * , A. A Heidari , A Gholamhosseini , H Najafzadeh
Abstract:   (3145 Views)
Administration of human anesthesia drugs in fish is mainly because of their high efficacy and availability as well as low price. In this study anesthetic effects of Ketamine and Acepromazine (0, 15 and 30 mg L-1) was evaluated in Shirbot (Tor grypus). Acepromazine concentrations prepared in 10 L containers in triplicates, then serial descending concentration of ketamine (for effective dose 20-400 mg L-1 and for lethal dose 320-900 mg L-1) were added to tank. Twelve fish were added to each container. Results analyzed with probit software and EC10, EC50 and EC90 as well as LC10, LC50 and LC90 of drugs in five minutes were measured. Results showed that no significant difference was seen in anesthesia efficacy, time of anesthesia induction and recovery time among groups (P>0.05), but lethal effects of Ketamine decreased significantly in Ketamin along with 15 mg L-1 Acepromazine (P<0.05). Then it can be concluded that Acepromazine increased the safety of Ketamine in Tor grypus at low doses
Keywords: Ketamine, Acepromazine, Tor grypus, Anesthesia
Full-Text [PDF 406 kb]   (869 Downloads)    
Type of Study: Original research papers | Subject: Treatment stategies with herbal or others
Received: 2018/11/15 | Accepted: 2019/11/10 | Published: 2019/11/20
References
1. Aboeldahab H., Samir R., Hosny H. & Omar A. (2011) Comparative study between propof, ketamine and their combination (ketofol) as an induction agent. Egyption Journal of Anaesthesia 27(3), 145-150. [DOI:10.1016/j.egja.2011.04.007]
2. Akbulut B., Çakmak E., Aksungur N. & Çavdar Y. (2011) Effect of exposure duration on time to recovery from anaesthesia of clove oil in juvenile of Russian sturgeon. Turkish Journal of Fisheries and Aquatic Sciences 11 (3), 80-90. [DOI:10.4194/1303-2712-v11_3_17]
3. Al-Hamdani A.H., Ebrahim S.K. & Mohammad F.K. (2010) Experimental xylazine-ketamine anesthesia in the common carp (Cyprinus carpio). Journal of Wildlife Diseases 46(2), 596-598. [DOI:10.7589/0090-3558-46.2.596] [PMID]
4. Anderson W.G., McKinley R.S. & Colavecchia M. (1997) The use of clove oil as an anesthetic for rainbow trout and its effects on swimming performance. North American Journal of Fisheries Managment 17(2), 301-307. https://doi.org/10.1577/1548-8675(1997)017<0301:TUOCOA>2.3.CO;2 [DOI:10.1577/1548-8675(1997)0172.3.CO;2]
5. Baboli M.J. & Anvari M. (2018) Determination of Optimum Weaning Time of Shirbot (Tor grypus Heckel, 1843) Larvae. Turkish Journal of Fisheries and Aquatic Sciences 18(12), 1371-1377. [DOI:10.4194/1303-2712-v18_12_05]
6. Bastos-Ramos W.P., Goncalves N.M. & Bacila M. (1998) Anesthesia and analgesia in Antarctic fish: an experimental approach. Archives of Veterinary Science 3(1), 30-38. [DOI:10.5380/avs.v3i1.3745]
7. Fleming G.J., Heard D.J., Floyd R.F. & Riggs A. (2003) Evaluation of propofol and medetomidine-ketamine for short-term immobilization of Gulf of Mexico sturgeon (Acipenser oxyrinchus de soti). Journal of Zoo and Wildlife Medicine 34(2), 153-158. [DOI:10.1638/1042-7260(2003)034[0153:EOPAMF]2.0.CO;2]
8. Hedayati A.A. (2018) Effects of 2-phenoxyethanol (2-PE) anesthesia on some haematological and biochemical indices of silver carp (Hypophthalmichthys molitrix). Iranian journal of fisheries sciences 17(1), 1-10.
9. Heidari B., Peyghan R., Esmaeilir-Rad A., Najafzadehvarzi. H., Bita S. & Poormehdi B. (2014) The effect of using different types of Magnesium Oxide and ketamine on anesthesia of in fingerling of common carp (Cyprinus carpio). Iranian Veterinary Journal 10(1), 23-30. [In Persian]
10. Kawai S., Takagi Y., Kaneko S. & Kurosawa T. (2011) Effect of three types of mixed anesthetic agents alternate to ketamine in mice. Experimental animals 60(5), 481-487. [DOI:10.1538/expanim.60.481] [PMID]
11. Lorrain D., Baccei C.S., Bristow L.J., Anderson J.J. & Varney M.A. (2003) Effects of ketamine and N-methyl-D-aspartate on glutamate and dopamine release in the rat prefrontal cortex: modulation by a group II selective metabotropic glutamate receptor agonist LY379268. Neuroscience journal 117(3), 697-706. [DOI:10.1016/S0306-4522(02)00652-8]
12. Marco P.D., Petochi T., Longobardi A., Priori A., Finoia M.G., Donadelli V. & Marino G. (2011) Efficacy of tricaine methanesulphonate, clove oil and medetomidine‐ketamine and their side effects on the physiology of sturgeon hybrid Acipenser naccarii × Acipenser baerii. Journal of Applied Ichtyiology 27(2), 611-617. [DOI:10.1111/j.1439-0426.2011.01701.x]
13. Martins T., Diniz E., Félix L.M. & Antunes L. (2018) Evaluation of anaesthetic protocols for laboratory adult zebrafish (Danio rerio). Public library of science one 13(5), e0197846. [DOI:10.1371/journal.pone.0197846] [PMID] [PMCID]
14. Matin S.M.A., Hossain M.A. & Hashim M.A. (2009) Clove oil anaesthesia in singhi (Heteropneustes fossilis) and lata (Channa punctatus) fish. Bangladesh journal of Veterinary medicine 26(2), 68-73. [DOI:10.3329/bvet.v26i2.4953]
15. Mirzargar S.S., Soltani M., Ahmadi M., Abrishamifar A., Bahonar A. & Yousefi P. (2011) Anesthetic effect of tricaine methanesulfonate, clove oil and electroanesthesia on lysozyme activity of Oncorhynchus mykiss. Iranian journal of fisheries sciences 10(3), 393-402. [In Persian]
16. Molina A.M., Moyano M.R., Serrano-Rodriguez J.M., Ayala N., Lora A.J., Serrano-Caballero J.M. (2015) Analyses of anaesthesia with ketamine combined with different sedatives in rats. Veterinary Medicine 60(7), 60-78. [DOI:10.17221/8384-VETMED]
17. Neiffer D.L. & Stamper M.A. (2009) Fish sedation, anesthesia, analgesia, and euthanasia: considerations, methods, and types of drugs. Institue for Laboratory Animal Reseaech Journal 50(4), 343-360. [DOI:10.1093/ilar.50.4.343] [PMID]
18. Nikpei M. (1996) Research project report: biological study of Tor grypus and Tor sharpie. Iranian fisheries science research institute 1, 52-64.
19. Nishimura L.T., Villela I.O.J., Carvalho L.L., Borges L.P.B., Silva M.A.M. & Mattos-Junior E. (2017) The Effect of Acepromazine Alone or in Combination with Methadone, Morphine, or Tramadol on Sedation and Selected Cardiopulmonary Variables in Sheep. Veterinary medicine international, 2017. [DOI:10.1155/2017/7507616] [PMID] [PMCID]
20. Peyghan R., Baniadam A. & Amirdad S.H. (2001) Using Ketamine and Xylasein hydrochloride for anesthesia of common carp (Cyprinus carpio). Pajohesh & sazandegi journal. 52:18-19. [In Persian]
21. Popovic N.P , Strunjak‐Perovic I., Coz‐Rakovac R., Barisic J., Jadan M., Persin Berakovic A. & Sauerborn Klobucar R. (2012) Tricaine methane‐sulfonate (MS‐222) application in fish anaesthesia. Journal of applied Ichthyology 28(4), 553-564. [DOI:10.1111/j.1439-0426.2012.01950.x]
22. Readman G.D., Owen S.F., Knowles T.G. & Murrell J.C. (2017) Species specific anaesthetics for fish anaesthesia and euthanasia. Scientific Reports 7(1), 1-7. [DOI:10.1038/s41598-017-06917-2] [PMID] [PMCID]
23. Riehl R., Kyzar E., Allain A., Green J., Hook M., Monnig L. & DiLeo, J. (2011) Behavioral and physiological effects of acute ketamine exposure in adult zebrafish. Neurotoxicology and Teratoloy Journal 33(6), 658-667. [DOI:10.1016/j.ntt.2011.05.011] [PMID]
24. Ross L.G. & Ross B. (2009) Anaesthetic and sedative techniques for aquatic animals. John Wiley & Sons. Third edition, 240 Pages. [DOI:10.1002/9781444302264]
25. Smith M.F. (1992) Capture and transportation of elasmobranchs, with emphasis on the grey nurse shark (Carcharias taurus). Journal of Marine and freshwater Research 43(1), 325-343. [DOI:10.1071/MF9920325]
26. Velisek J., Svobodova Z., Piackova V., Groch L. & Nepejchalova L. (2005) Effects of clove oil anaesthesia on common carp (Cyprinus carpio L.). Veterinary medicine 50(6), 269-275. [DOI:10.17221/5623-VETMED]
27. Vesal N., Sarchahi A.A., Nikahval B. & Karampour A. (2011) Clinical evaluation of the sedative properties of acepromazine xylazine combinations with or without atropine and their effects on physiologic values in dogs. Veterinarski arhiv 81(4), 485-498.
28. Zahl I.H., Kiessling A., Samuelsen O.B. & Hansen M.K. (2009) Anaesthesia of Atlantic cod (Gadus morhua) effect of pre-anaesthetic sedation, and importance of body weight, temperature and stress. Aquaculture 295(1-2), 52-59. [DOI:10.1016/j.aquaculture.2009.06.019]



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